Modelling fibrinolysis: a 3D stochastic multiscale model.

Abstract

Fibrinolysis, the proteolytic degradation of the fibrin fibres that stabilize blood clots, is initiated when tissue-type plasminogen activator (tPA) activates plasminogen to plasmin, the main fibrinolytic enzyme. Many experiments have shown that coarse clots made of thick fibres lyse more quickly than fine clots made of thin fibres, despite the fact that… (More)
DOI: 10.1093/imammb/dqs029

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