Modelling epidemics with fractional-dose vaccination in response to limited vaccine supply.

  title={Modelling epidemics with fractional-dose vaccination in response to limited vaccine supply.},
  author={Zhimin Chen and Kaihui Liu and Xiuxiang Liu and Yijun Lou},
  journal={Journal of theoretical biology},
3 Citations
Optimizing COVID-19 vaccination programs during vaccine shortages
Bifurcations Induced by Self-connection Delay in High-Order Fractional Neural Networks
This paper discusses the problem of bifurcations for a delayed fractional-order neural networks (FONNs) with multiple neurons and declares that self-connection delay immensely affects the stability and b ifurcation of the developed FONNs.
Analysis of Multiterm Initial Value Problems with Caputo–Fabrizio Derivative
In this paper, we discuss the solvability of a class of multiterm initial value problems involving the Caputo–Fabrizio fractional derivative via the Laplace transform. We derive necessary and


Impact of viral drift on vaccination dynamics and patterns of seasonal influenza
Simulation results show that the pattern of large seasonal epidemics is strongly correlated with the duration of specific cross-protection immunity induced by natural infection, and a mathematical model linked different intra-seasonal dynamics of vaccination and infection finds that the protection efficacy of vaccine is a parameter that could influence these patterns.
Transmission Dynamics of an Influenza Model with Vaccination and Antiviral Treatment
The findings imply that higher levels of treatment may lead to an increase of epidemic size, and the extent to which this occurs depends on other factors such as the rates of vaccination and resistance development.
Optimal isolation strategies of emerging infectious diseases with limited resources.
This work shows that a classical deterministic SIR model modified to take into account of limited resources for diagnostic confirmation/medical isolation leads to four different scenarios for optimal isolation strategies, and obtains analytic solutions for the optimal control problem that minimize the outbreak size under the assumption oflimited resources for isolation.
A note on the use of influenza vaccination strategies when supply is limited.
The 2009 A (H1N1) influenza pandemic was rather atypical and optimal control theory is used to explore the impact of some of the constraints faced by most nations in implementing a public health policy that tried to meet the challenges that come from having access to a limited vaccine supply.
Optimal control of epidemics with limited resources
This work provides optimal control policies for an isolation only model, a vaccination only model and a combined isolation–vaccination model (or mixed model) under the assumption that there are limited control resources.
Pertussis immunity and epidemiology: mode and duration of vaccine-induced immunity
Mechanistic transmission models are used to examine regional time series incidence data from Italy in the period immediately following the introduction of acellular pertussis (aP) vaccine and identify key data gaps: sources of data that can supply the information needed to eliminate remaining uncertainties.
Long-Term Protection After Fractional-Dose Yellow Fever Vaccination
The rationale for the Strategic Advisory Group of Experts, the principal advisory group to the World Health Organization for vaccines and immunization, to recommend a radical yet necessary switch to administration of a fractional dose instead of a full dose of yellow fever vaccine for mass vaccinations in emergency situations is provided.