Modelling dysplasia detection in ulcerative colitis: clinical implications of surveillance intensity.

@article{Awais2009ModellingDD,
  title={Modelling dysplasia detection in ulcerative colitis: clinical implications of surveillance intensity.},
  author={Dr. Muhammad Awais and Corey Allan Siegel and Peter D. R. Higgins},
  journal={Gut},
  year={2009},
  volume={58 11},
  pages={
          1498-503
        }
}
BACKGROUND Endoscopic surveillance of chronic colitis uses random biopsies to find dysplastic fields. Enhanced endoscopic methods are more sensitive for dysplasia detection, but their specificity for colorectal cancer risk is unknown. AIMS To develop a mathematical model of the sensitivity of random biopsy surveillance, and determine the implications of negative, a single positive, or multiple positive biopsies for dysplasia, and compare the detection threshold to that detectable by enhanced… CONTINUE READING
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Probability of occult cancer in ulcerative colitis with dysplasia : a modern assessment

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