Modelling bacterial speciation

@article{Hanage2006ModellingBS,
  title={Modelling bacterial speciation},
  author={William P. Hanage and Brian G. Spratt and Katherine Turner and Christophe Fraser},
  journal={Philosophical Transactions of the Royal Society B: Biological Sciences},
  year={2006},
  volume={361},
  pages={2039 - 2044}
}
A central problem in understanding bacterial speciation is how clusters of closely related strains emerge and persist in the face of recombination. We use a neutral Fisher-Wright model in which genotypes, defined by the alleles at 140 house-keeping loci, change in each generation by mutation or recombination, and examine conditions in which an initially uniform population gives rise to resolved clusters. Where recombination occurs at equal frequency between all members of the population, we… CONTINUE READING

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