Modeling toxicodynamic effects of trichloroethylene on liver in mouse model of autoimmune hepatitis.

Abstract

Chronic exposure to industrial solvent and water pollutant trichloroethylene (TCE) in female MRL+/+mice generates disease similar to human autoimmune hepatitis. The current study was initiated to investigate why TCE-induced autoimmunity targeted the liver. Compared to other tissues the liver has an unusually robust capacity for repair and regeneration. This… (More)
DOI: 10.1016/j.taap.2014.07.003

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