Modeling the toxicokinetics of inhaled toluene in rats: influence of physical activity and feeding status.

@article{Kenyon2008ModelingTT,
  title={Modeling the toxicokinetics of inhaled toluene in rats: influence of physical activity and feeding status.},
  author={Elaina M. Kenyon and Vernon A. Benignus and Christopher R Eklund and Jerry W. Highfill and Wendy M. Oshiro and Tracey E Samsam and Philip J. Bushnell},
  journal={Journal of toxicology and environmental health. Part A},
  year={2008},
  volume={71 4},
  pages={249-65}
}
Toluene is found in petroleum-based fuels and used as a solvent in consumer products and industrial applications. The critical effects following inhalation exposure involve the brain and nervous system in both humans and experimental animals, whether exposure duration is acute or chronic. The goals of this physiologically based pharmacokinetic (PBPK) model… CONTINUE READING