Modeling the slowing of neurofilament transport along the mouse sciatic nerve.

@article{Jung2009ModelingTS,
  title={Modeling the slowing of neurofilament transport along the mouse sciatic nerve.},
  author={Peter Jung and Andy Brown},
  journal={Physical biology},
  year={2009},
  volume={6 4},
  pages={046002}
}
Neurofilaments are transported along axons in the slow component of axonal transport. The average rate of movement is generally quoted as several millimeters or tenths of a millimeter per day, but this rate is known to decrease while the neurofilaments are in transit due to spatial and temporal factors that are not understood. We have previously presented a stochastic model for neurofilament movement in vivo based on the transport kinetics of single neurofilaments observed by time-lapse… CONTINUE READING