Modeling the impact of DNA methylation on the evolution of BRCA1 in mammals.

@article{Huttley2004ModelingTI,
  title={Modeling the impact of DNA methylation on the evolution of BRCA1 in mammals.},
  author={Gavin A. Huttley},
  journal={Molecular biology and evolution},
  year={2004},
  volume={21 9},
  pages={1760-8}
}
The modified base 5-methylcytosine ((m)C) plays an important functional role in the biology of mammals as an epigenetic modification and appears to exert a striking impact on the molecular evolution of mammal genomes. The collective epigenetic functions of (m)C revolve around its effect on gene transcription, while the influence of this modified base on the… CONTINUE READING