Modeling the hemodynamic response to brain activation

@article{Buxton2004ModelingTH,
  title={Modeling the hemodynamic response to brain activation},
  author={R. Buxton and K. Uludağ and D. Dubowitz and T. Liu},
  journal={NeuroImage},
  year={2004},
  volume={23},
  pages={s220-s233}
}
Neural activity in the brain is accompanied by changes in cerebral blood flow (CBF) and blood oxygenation that are detectable with functional magnetic resonance imaging (fMRI) techniques. In this paper, recent mathematical models of this hemodynamic response are reviewed and integrated. Models are described for: (1) the blood oxygenation level dependent (BOLD) signal as a function of changes in cerebral oxygen extraction fraction (E) and cerebral blood volume (CBV); (2) the balloon model… Expand
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