Modeling the effects of HIV-1 virions and proteins on Fas-induced apoptosis of infected cells

Abstract

We report a first in modeling and simulation of the effects of the HIV proteins on the (caspase dependent) apoptotic pathway in infected cells. This work is novel and is an extension on the recent reports and clarifications on the FAS apoptotic pathway from the literature. We have gathered most of the reaction rates and initial conditions from the… (More)

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