Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro.

@article{Yen2006ModelingTE,
  title={Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro.},
  author={Y E Yen and Fang Liao and C. -W. Hsiao and Chuan-Liang Kao and Yee-Chun Chen and Betty A Wu-Hsieh},
  journal={Journal of virology},
  year={2006},
  volume={80 6},
  pages={2684-93}
}
The clinical picture of severe acute respiratory syndrome (SARS) is characterized by pulmonary inflammation and respiratory failure, resembling that of acute respiratory distress syndrome. However, the events that lead to the recruitment of leukocytes are poorly understood. To study the cellular response in the acute phase of SARS coronavirus (SARS-CoV)-host cell interaction, we investigated the induction of chemokines, adhesion molecules, and DC-SIGN (dendritic cell-specific ICAM-3-grabbing… CONTINUE READING

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