Modeling the dynamics of oral poliovirus vaccine cessation.

Abstract

BACKGROUND Oral poliovirus vaccine (OPV) results in an ongoing burden of poliomyelitis due to vaccine-associated paralytic poliomyelitis and circulating vaccine-derived polioviruses (cVDPVs). This motivates globally coordinated OPV cessation after wild poliovirus eradication. METHODS We modeled poliovirus transmission and OPV evolution to characterize the… (More)
DOI: 10.1093/infdis/jit845

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