Modeling the diffusion-erosion crossover dynamics in drug release.

  title={Modeling the diffusion-erosion crossover dynamics in drug release.},
  author={M{\'a}rcio S. Gomes-Filho and F. A. Oliveira and Marco Aur'elio Alves Barbosa},
  journal={Physical review. E},
  volume={105 4-1},
A computational model is proposed to investigate drug delivery systems in which erosion and diffusion mechanisms are participating in the drug release process. Our approach allowed us to analytically estimate the crossover point between those mechanisms through the value of the parameter b (b_{c}=1) and the scaling behavior of parameter τ on the Weibull function, exp[-(t/τ)^{b}], used to adjust drug release data in pharmaceutical literature. Numerical investigations on the size dependence of… 

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