Modeling the Role of Mid-Wavelength Cones in Circadian Responses to Light

@article{DkhissiBenyahya2007ModelingTR,
  title={Modeling the Role of Mid-Wavelength Cones in Circadian Responses to Light},
  author={Ouria Dkhissi-Benyahya and Claude Gronfier and Wena De Vanssay and Fr{\'e}d{\'e}ric Flamant and Howard M. Cooper},
  journal={Neuron},
  year={2007},
  volume={53},
  pages={677-687}
}
Nonvisual responses to light, such as photic entrainment of the circadian clock, involve intrinsically light-sensitive melanopsin-expressing ganglion cells as well as rod and cone photoreceptors. However, previous studies have been unable to demonstrate a specific contribution of cones in the photic control of circadian responses to light. Using a mouse model that specifically lacks mid-wavelength (MW) cones we show that these photoreceptors play a significant role in light entrainment and in… CONTINUE READING
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