Corpus ID: 119340559

Modeling the Role of Gap Junction Transport Characteristics in the Action Potential Propagation

@article{Irurzun2018ModelingTR,
  title={Modeling the Role of Gap Junction Transport Characteristics in the Action Potential Propagation},
  author={Isabel M Irurzun and Magdalena M. Defeo},
  journal={arXiv: Pattern Formation and Solitons},
  year={2018}
}
  • I. Irurzun, M. Defeo
  • Published 1 September 2018
  • Physics
  • arXiv: Pattern Formation and Solitons
We generalize the Cable Model to describe the transport characteristics of the gap junctions coupling adjacent cells in the heart muscle. Our model takes into account recent experimental information about the time dependence of the junctional current and modifies the connections between cells. It can be used with whatever excitable model is used to represent the cell. We show that by modulating the gap junction transport characteristics, it is possible to either suppress or produce meandering… Expand

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