Modeling the Kinetics of Integrin Receptor Binding to Hepatic Extracellular Matrix Proteins

The composition of the extracellular matrix (ECM) proteins and the expression of their cognate receptors dictate cell behavior and dynamics. In particular, the interactions of ECM proteins with integrin receptors are key mediators of these cellular processes, playing a crucial role in the progression of several diseases of the liver, including inflammation… CONTINUE READING