Modeling the Heart--from Genes to Cells to the Whole Organ

@article{Noble2002ModelingTH,
  title={Modeling the Heart--from Genes to Cells to the Whole Organ},
  author={Denis Noble},
  journal={Science},
  year={2002},
  volume={295},
  pages={1678 - 1682}
}
  • D. Noble
  • Published 1 March 2002
  • Biology, Medicine
  • Science
Successful physiological analysis requires an understanding of the functional interactions between the key components of cells, organs, and systems, as well as how these interactions change in disease states. This information resides neither in the genome nor even in the individual proteins that genes code for. It lies at the level of protein interactions within the context of subcellular, cellular, tissue, organ, and system structures. There is therefore no alternative to copying nature and… 
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