Modeling the Electrophoresis of Short Duplex DNA : Counterions K + and Tris

@inproceedings{MazurModelingTE,
  title={Modeling the Electrophoresis of Short Duplex DNA : Counterions K + and Tris},
  author={Suzann Mazur and Chuanying Chen and Stuart A. Allison}
}
The electrophoretic mobility of short 18 and 20 bp duplex DNAs is modeled by an iterative boundary element procedure that numerically solves the coupled Poisson, low Reynolds Number Navier -Stokes, and ion transport equations. Both capped cylinder (CC) and “detailed” models derived from the secondary structure of the fragments are examined. Translation -rotation coupling is examined with regard to the transport of the detailed models, and it is concluded that this coupling has very little… CONTINUE READING

References

Publications referenced by this paper.

The darkly shaded multibead structures represent Tris + counterions in complex with DNA . The complex has been energy minimized using SYBYL

  • S. A. Allison
  • Macromolecules
  • 1999

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