Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.

Abstract

Purpose: To demonstrate that a mathematical model can be used to quantitatively understand tumor cellular dynamics during a course of radiotherapy and to predict the likelihood of local control as a function of dose and treatment fractions.Experimental Design: We model outcomes for early-stage, localized non-small cell lung cancer (NSCLC), by fitting a… (More)
DOI: 10.1158/1078-0432.CCR-16-3277

Topics

Cite this paper

@article{Jeong2017ModelingTC, title={Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.}, author={Jeho Jeong and Jung Hun Oh and Jan-Jakob Sonke and Jos{\'e} S A Belderbos and Jeffrey D. Bradley and Andrew N. Fontanella and Shyam S D Rao and Joseph O. Deasy}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2017}, volume={23 18}, pages={5469-5479} }