Modeling the Biological Nanopore Instrument for Biomolecular State Estimation


The nanopore is a powerful tool for probing biomolecular interactions at the single-molecule level, and shows great promise commercially as a next-generation deoxyribonucleic acid (DNA) sequencing technology. Coupling active voltage control with the nanopore has expanded its capabilities, for example, by allowing precise manipulation of DNA-enzyme complexes… (More)
DOI: 10.1109/TCST.2012.2224349


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