Modeling strategies for enantiomers separation by SMB chromatography

@article{Pais1998ModelingSF,
  title={Modeling strategies for enantiomers separation by SMB chromatography},
  author={L. Pais and J. Loureiro and A. E. Rodrigues},
  journal={Aiche Journal},
  year={1998},
  volume={44},
  pages={561-569}
}
  • L. Pais, J. Loureiro, A. E. Rodrigues
  • Published 1998
  • Chemistry
  • Aiche Journal
    • Modeling strategies for simulated moving bed adsorbers were studied to compare the simulated moving bed model (SMB) that considers the real shift of the injection and collection points to the true moving bed approach (TMB) that considers liquid and solid flow in opposite directions. The prediction of these two models is compared in terms of steady-state performance, steady-state internal concentration profiles, and transient behavior of the extract and raffinate purities. The influence of the… CONTINUE READING
    View via Publisher
    bibliotecadigital.ipb.pt
    144 Citations
    Highly Influential Citations
    5
    Background Citations
    21
    Methods Citations
    18
    Results Citations
    1

    Figures and Tables from this paper

    Figures and Tables

    144 Citations
    Citation Type

    Citation Type

    The use of simulated moving bed in chromatographic separation: Study of the SMB* configuration
    • 8
    Chiral separation by SMB chromatography
    • 42
    • PDF
    The use of simulated moving bed in chromatographic separation: study of the SMB configuration
    SMB enantioseparation: Process development, modeling, and operating conditions
    • 33
    Design of SMB Chiral Separations Using the Concept of Separation Volume
    • 42
    • PDF
    Experimental Study of Continuous Separation of Enantiomers by Simulated Moving Bed Chromatography
    Enantiomers separation by simulated moving bed chromatography. Non-instantaneous equilibrium at the solid-fluid interface.
    • 19
    • PDF
    Separation of ternary mixtures by pseudo-simulated moving bed chromatography.
    • 59
    Enantioseparation of racemic mandelic acid by simulated moving bed chromatography using Chiralcel-OD column
    • 2
    Principles of Simulated Moving Bed
    • 5

    References

    SHOWING 1-10 OF 36 REFERENCES
    Modeling and Simulation of SMB Technology for Pharmaceutical and Fine Chemical Applications
    • 3
    Comparison of the specific productivity of different chiral stationary phases used for simulated moving-bed chromatography
    • 61
    Preparative scale enantioseparation of a chiral epoxide: Comparison of liquid chromatography and simulated moving bed adsorption technology
    • 91
    Separation of 1,1'-bi-2-naphthol enantiomers by continuous chromatography in simulated moving bed
    • 92
    • PDF
    Analytical solution for the linear ideal model of simulated moving bed chromatography
    • 74
    Simulated moving bed chromatography. Effects of axial dispersion and mass transfer under linear conditions
    • 30
    Evaluation of simulated moving bed chromatography for pharmaceutical process development
    • 71
    Simulated moving bed under linear conditions: Experimental vs. calculated results
    • 32
    Applications of simulated moving-bed chromatography to the separation of the enantiomers of chiral drugs
    • 124
    Modeling, simulation and operation of a simulated moving bed for continuous chromatographic separation of 1,1′-bi-2-naphthol enantiomers
    • 64
    • PDF