Modeling spontaneous activity across an excitable epithelium: Support for a coordination scenario of early neural evolution

@inproceedings{Wiljes2015ModelingSA,
  title={Modeling spontaneous activity across an excitable epithelium: Support for a coordination scenario of early neural evolution},
  author={Oltman O de Wiljes and Ronald A. J. van Elburg and Michael Biehl and Fred A Keijzer},
  booktitle={BMC Neuroscience},
  year={2015}
}
Internal coordination models hold that early nervous systems evolved in the first place to coordinate internal activity at a multicellular level, most notably the use of multicellular contractility as an effector for motility. A recent example of such a model, the skin brain thesis, suggests that excitable epithelia using chemical signaling are a potential candidate as a nervous system precursor. We developed a computational model and a measure for whole body coordination to investigate the… CONTINUE READING
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