Modeling regulatory networks to understand plant development: small is beautiful.

@article{Middleton2012ModelingRN,
  title={Modeling regulatory networks to understand plant development: small is beautiful.},
  author={Alistair M. Middleton and Etienne Farcot and Markus R. Owen and Teva Vernoux},
  journal={The Plant cell},
  year={2012},
  volume={24 10},
  pages={3876-91}
}
We now have unprecedented capability to generate large data sets on the myriad genes and molecular players that regulate plant development. Networks of interactions between systems components can be derived from that data in various ways and can be used to develop mathematical models of various degrees of sophistication. Here, we discuss why, in many cases, it is productive to focus on small networks. We provide a brief and accessible introduction to relevant mathematical and computational… CONTINUE READING