Modeling radiation dosimetry to predict cognitive outcomes in pediatric patients with CNS embryonal tumors including medulloblastoma.

@article{Merchant2006ModelingRD,
  title={Modeling radiation dosimetry to predict cognitive outcomes in pediatric patients with CNS embryonal tumors including medulloblastoma.},
  author={Thomas E. Merchant and Erin N. Kiehna and Chenghong Li and Hemant Shukla and Saikat Sengupta and Xiaoping P Xiong and Amar Gajjar and Raymond K. Mulhern},
  journal={International journal of radiation oncology, biology, physics},
  year={2006},
  volume={65 1},
  pages={210-21}
}
PURPOSE Model the effects of radiation dosimetry on IQ among pediatric patients with central nervous system (CNS) tumors. METHODS AND MATERIALS Pediatric patients with CNS embryonal tumors (n = 39) were prospectively evaluated with serial cognitive testing, before and after treatment with postoperative, risk-adapted craniospinal irradiation (CSI) and conformal primary-site irradiation, followed by chemotherapy. Differential dose-volume data for 5 brain volumes (total brain, supratentorial… CONTINUE READING

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