Modeling of fluorine-18-6-fluoro-L-Dopa in humans.

  title={Modeling of fluorine-18-6-fluoro-L-Dopa in humans.},
  author={Lindi M. Wahl and Claude Nahmias},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={37 3},
UNLABELLED Fluorine-18-6-fluoro-L-Dopa (F-Dopa) has been used successfully to evaluate striatal dopaminergic function in humans. The kinetic analysis of F-Dopa studies, however, is confounded by the presence of [18F]6-fluoro-3-O-methyl-L-Dopa (OMFD), the major metabolite of F-Dopa formed in the periphery that crosses the blood-brain barrier. We present… CONTINUE READING