Modeling of degradation and drug release from a biodegradable stent coating.

  title={Modeling of degradation and drug release from a biodegradable stent coating.},
  author={Santosh T Prabhu and Syed F A Hossainy},
  journal={Journal of biomedical materials research. Part A},
  volume={80 3},
Biodegradable polymeric coatings on cardiovascular stents can be used for local delivery of therapeutic agents to diseased coronary arteries after stenting procedures. This can minimize the occurrence of clinically adverse events such as restenosis after stent implantation. A validated mathematical model can be a very important tool in the design and development of such coatings for drug delivery. The model should incorporate the important physicochemical processes responsible for the polymer… CONTINUE READING


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