Modeling mitochondrial dysfunctions in the brain: from mice to men

Abstract

The biologist Lewis Thomas once wrote: “my mitochondria comprise a very large proportion of me. I cannot do the calculation, but I suppose there is almost as much of them in sheer dry bulk as there is the rest of me”. As humans, or indeed as any mammal, bird, or insect, we contain a specific molecular makeup that is driven by vast numbers of these miniscule… (More)
DOI: 10.1007/s10545-011-9375-8

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