Modeling metabolic systems: the need for dynamics

@inproceedings{Song2013ModelingMS,
  title={Modeling metabolic systems: the need for dynamics},
  author={Hyun-Seob Song and Frank DeVilbiss and Doraiswami Ramkrishna},
  year={2013}
}
Living organisms exhibit dynamic shifts of metabolic pathways to cope with various perturbations. Such temporal change of modus operandi is one of the key mechanisms characterizing metabolic behavior. In this review, we highlight the importance and potential of dynamic modeling in understanding and harnessing metabolic systems, in particular, for bioprocess optimization and metabolic engineering. In a field that harbors a variety of approaches, their relative assessment calls for appropriate… CONTINUE READING
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