Modeling metabolic response to changes of enzyme amount in yeast glycolysis

@inproceedings{Yang2010ModelingMR,
  title={Modeling metabolic response to changes of enzyme amount in yeast glycolysis},
  author={Xuelian Yang and Lin Xu and Ming Yan},
  year={2010}
}
Based on the work of Hynne et al. (2001), in an in silico model of glycolysis, Saccharomyces cerevisiae is established by introducing an enzyme amount multiple factor (.) into the kinetic equations. The model is aimed to predict the metabolic response to the change of enzyme amount. With the help of .α, the amounts of twelve enzymes were altered by different multiples from their initial values. Then twenty metabolite concentrations were monitored and analyzed. The prediction of metabolite… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 17 REFERENCES

The allosteric regulation of pyruvate kinase.

  • The Journal of biological chemistry
  • 2000
VIEW 2 EXCERPTS

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