Modeling ion permeation through batrachotoxin-modified Na+ channels from rat skeletal muscle with a multi-ion pore.

@article{Ravindran1992ModelingIP,
  title={Modeling ion permeation through batrachotoxin-modified Na+ channels from rat skeletal muscle with a multi-ion pore.},
  author={A D Ravindran and H Kwieciński and Osvaldo Alvarez and George Eisenman and Edward G. Moczydlowski},
  journal={Biophysical journal},
  year={1992},
  volume={61 2},
  pages={494-508}
}
The mechanism of ion permeation through Na+ channels that have been modified by batrachotoxin (BTX) and inserted into planar bilayers has been generally described by models based on single-ion occupancy, with or without an influence of negative surface charge, depending on the tissue source. For native Na+ channels there is evidence suggestive of a multi… CONTINUE READING