Modeling interindividual variation in physiological factors used in PBPK models of humans.

  title={Modeling interindividual variation in physiological factors used in PBPK models of humans.},
  author={Paul S. Price and Rory B. Conolly and Christine F. Chaisson and Elizabeth A Gross and John S. Young and Eric T Mathis and Douglas R Tedder},
  journal={Critical reviews in toxicology},
  volume={33 5},
Modeling interindividual variation in internal doses in humans using PBPK models requires data on the variation in physiological parameters across the population of interest. These data should also reflect the correlations between the values of the various parameters in a person. In this project, we develop a source of data for human physiological parameters where (1) the parameter values for an individual are correlated with one another, and (2) values of parameters capture interindividual… CONTINUE READING
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Modeling Inter-individual Variation in Physiological Factors Used in PBPK Models of Humans

  • P. S. Price, R. B. Conolly, C. F. Chaisson, J. S. Young
  • Critical Reviews in Toxicology
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Species Differences in Bioavailability of Inhaled Vapors and Gases

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