Modeling human cancer cachexia in colon 26 tumor-bearing adult mice

@inproceedings{Talbert2014ModelingHC,
  title={Modeling human cancer cachexia in colon 26 tumor-bearing adult mice},
  author={Erin E. Talbert and Gregory A. Metzger and Wei A. He and Denis C. Guttridge},
  booktitle={Journal of cachexia, sarcopenia and muscle},
  year={2014}
}
BackgroundMuscle wasting is a profound side effect of advanced cancer. Cancer-induced cachexia decreases patient quality of life and is associated with poor patient survival. Currently, no clinical therapies exist to treat cancer-induced muscle wasting. Although cancers commonly associated with cachexia occur in older individuals, the standard animal models used to elucidate the causes of cachexia rely on juvenile mice.MethodsIn an effort to better model human cancer cachexia, we determined… CONTINUE READING
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