Modeling hepatitis C virus dynamics: liver regeneration and critical drug efficacy.

@article{Dahari2007ModelingHC,
  title={Modeling hepatitis C virus dynamics: liver regeneration and critical drug efficacy.},
  author={Harel Dahari and Arthur Lo and Ruy M. Ribeiro and Alan S. Perelson},
  journal={Journal of theoretical biology},
  year={2007},
  volume={247 2},
  pages={371-81}
}
Mathematical models for hepatitis C viral (HCV) RNA kinetics have provided a means of evaluating the antiviral effectiveness of therapy, of estimating parameters such as the rate of HCV RNA clearance, and they have suggested mechanism of action against HCV for both interferon and ribavirin. Nevertheless, the model that was originally formulated by Neumann et al. [1998. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. Science 282 (5386), 103-107] is… CONTINUE READING
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