Modeling feedback loops of the Mammalian circadian oscillator.

@article{BeckerWeimann2004ModelingFL,
  title={Modeling feedback loops of the Mammalian circadian oscillator.},
  author={Sabine Becker-Weimann and Jana Wolf and Hanspeter Herzel and Achim Kramer},
  journal={Biophysical journal},
  year={2004},
  volume={87 5},
  pages={3023-34}
}
The suprachiasmatic nucleus governs daily variations of physiology and behavior in mammals. Within single neurons, interlocked transcriptional/translational feedback loops generate circadian rhythms on the molecular level. We present a mathematical model that reflects the essential features of the mammalian circadian oscillator to characterize the differential roles of negative and positive feedback loops. The oscillations that are obtained have a 24-h period and are robust toward parameter… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 134 citations. REVIEW CITATIONS
66 Citations
55 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 66 extracted citations

134 Citations

01020'07'10'13'16
Citations per Year
Semantic Scholar estimates that this publication has 134 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 55 references

Similar Papers

Loading similar papers…