Modeling dynamics in diseased cardiac tissue: Impact of model choice.

  title={Modeling dynamics in diseased cardiac tissue: Impact of model choice.},
  author={Tanmay A. Gokhale and Eli Medvescek and Craig S. Henriquez},
  volume={27 9},
Cardiac arrhythmias have been traditionally simulated using continuous models that assume tissue homogeneity and use a relatively large spatial discretization. However, it is believed that the tissue fibrosis and collagen deposition, which occur on a micron-level, are critical factors in arrhythmogenesis in diseased tissues. Consequently, it remains unclear how well continuous models, which use averaged electrical properties, are able to accurately capture complex conduction behaviors such as… CONTINUE READING
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