Modeling disease trajectory in Duchenne muscular dystrophy

@article{Rooney2020ModelingDT,
  title={Modeling disease trajectory in Duchenne muscular dystrophy},
  author={W. Rooney and Yosef A. Berlow and W. Triplett and S. Forbes and R. Willcocks and Dah-Jyuu Wang and I. Arpan and H. Arora and C. Senesac and D. Lott and G. Tennekoon and R. Finkel and B. Russman and E. Finanger and Saptarshi Chakraborty and E. O’Brien and Brendan Moloney and A. Barnard and H. Sweeney and M. Daniels and G. Walter and K. Vandenborne},
  journal={Neurology},
  year={2020},
  volume={94},
  pages={e1622 - e1633}
}
Objective To quantify disease progression in individuals with Duchenne muscular dystrophy (DMD) using magnetic resonance biomarkers of leg muscles. Methods MRI and magnetic resonance spectroscopy (MRS) biomarkers were acquired from 104 participants with DMD and 51 healthy controls using a prospective observational study design with patients with DMD followed up yearly for up to 6 years. Fat fractions (FFs) in vastus lateralis and soleus muscles were determined with 1H MRS. MRI quantitative T2… Expand
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