Modeling depression in animal models.

@article{Overstreet2012ModelingDI,
  title={Modeling depression in animal models.},
  author={David H. Overstreet},
  journal={Methods in molecular biology},
  year={2012},
  volume={829},
  pages={
          125-44
        }
}
Animal models and preclinical tests have played large roles in the development of antidepressant drugs and are likely to continue to play important roles. In the present communication, the main animal models of depression have been described and reviewed. These models include the Flinders sensitive line (FSL) rat, the Wistar Kyoto (WKY) rat, the fawn-hooded (FH) rat, and the learned helpless (LH) rat. In addition, the materials used to assess the behavior of these rats, including swim tanks… CONTINUE READING
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