Modeling cocaine-induced alterations in organization and patterning of neocortical development using human pluripotent stem cells

@article{Lee2015ModelingCA,
  title={Modeling cocaine-induced alterations in organization and patterning of neocortical development using human pluripotent stem cells},
  author={Chun-Ting Lee and Abigail A. Kindberg and W. Freed and T. Su},
  journal={Stem Cell and Translational Investigation},
  year={2015},
  volume={2}
}
Disorders of human neocortical development are particularly difficult to study by using animal models because of the marked complexity and unique features of the human cerebral cortex. Developmental effects of cocaine, as well as other drugs and toxins, are particularly challenging to study due to complicating factors such as variations in genetic background, time of exposure, and exposure to multiple substances. Studies aimed at elucidating the effects of cocaine on fetal brain development… Expand

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