Modeling cancer detection: tumor size as a source of information on unobservable stages of carcinogenesis.

@article{Bartoszynski2001ModelingCD,
  title={Modeling cancer detection: tumor size as a source of information on unobservable stages of carcinogenesis.},
  author={Robert Bartoszynski and L. Edler and Leonid Hanin and Annette Kopp-Schneider and Lyudmila Pavlova and A. Tsodikov and Alexey Zorin and Andrei Yu Yakovlev},
  journal={Mathematical biosciences},
  year={2001},
  volume={171 2},
  pages={
          113-42
        }
}
This paper is concerned with modern approaches to mechanistic modeling of the process of cancer detection. Measurements of tumor size at diagnosis represent a valuable source of information to enrich statistical inference on the processes underlying tumor latency. One possible way of utilizing this information is to model cancer detection as a quantal response variable. In doing so, one relates the chance of detecting a tumor to its current size. We present various theoretical results emerging… CONTINUE READING

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