Modeling based on the structure of vicilins predicts a histidine cluster in the active site of oxalate oxidase

@article{Gane1998ModelingBO,
  title={Modeling based on the structure of vicilins predicts a histidine cluster in the active site of oxalate oxidase},
  author={P. Gane and Jim M. Dunwell and Jim Warwickr},
  journal={Journal of Molecular Evolution},
  year={1998},
  volume={46},
  pages={488-493}
}
It is known that germin, which is a marker of the onset of growth in germinating wheat, is an oxalate oxidase, and also that germins possess sequence similarity with legumin and vicilin seed storage proteins. These two pieces of information have been combined in order to generate a 3D model of germin based on the structure of vicilin and to examine the model with regard to a potential oxalate oxidase active site. A cluster of three histidine residues has been located within the conserved… CONTINUE READING
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