Modeling baroreflex regulation of heart rate during orthostatic stress.

  title={Modeling baroreflex regulation of heart rate during orthostatic stress.},
  author={Mette S. Olufsen and H. T. Tran and Johnny T. Ottesen and Lewis A. Lipsitz and Vera Novak},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  volume={291 5},
During orthostatic stress, arterial and cardiopulmonary baroreflexes play a key role in maintaining arterial pressure by regulating heart rate. This study presents a mathematical model that can predict the dynamics of heart rate regulation in response to postural change from sitting to standing. The model uses blood pressure measured in the finger as an input to model heart rate dynamics in response to changes in baroreceptor nerve firing rate, sympathetic and parasympathetic responses… CONTINUE READING
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