Modeling and experiment yields the structure of acireductone dioxygenase from Klebsiella pneumoniae

Abstract

Here we report the structure of acireductone dioxygenase (ARD), the first determined for a new family of metalloenzymes. ARD represents a branch point in the methionine salvage pathway leading from methylthioadenosine to methionine and has been shown to catalyze different reactions depending on the type of metal ion bound in the active site. The solution… (More)
DOI: 10.1038/nsb863

Topics

7 Figures and Tables

Slides referencing similar topics