Modeling and control of crystal shape in continuous protein crystallization


In this work, a continuous crystallization process with a fines trap is modeled in an effort to produce tetragonal hen-egg-white (HEW) lysozyme crystals with a desired shape distribution. The crystal shape of tetragonal lysozyme crystals is defined by the aspect ratio of the crystal heights in the direction of the (110) and (101) faces. A kinetic Monte… (More)


14 Figures and Tables