Modeling and Simulation of Genetic Regulatory Systems: A Literature Review

@article{Jong2002ModelingAS,
  title={Modeling and Simulation of Genetic Regulatory Systems: A Literature Review},
  author={Hidde de Jong},
  journal={Journal of Computational Biology},
  year={2002},
  volume={9},
  pages={67-103}
}
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between DNA, RNA, proteins, and small molecules. As most genetic regulatory networks of interest involve many components connected through interlocking positive and negative feedback loops, an intuitive… CONTINUE READING
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