Modeling Active Mechanosensing in Cell-Matrix Interactions.

  title={Modeling Active Mechanosensing in Cell-Matrix Interactions.},
  author={Bin Chen and Baohua Ji and Huajian Gao},
  journal={Annual review of biophysics},
Cells actively sense the mechanical properties of the extracellular matrix, such as its rigidity, morphology, and deformation. The cell-matrix interaction influences a range of cellular processes, including cell adhesion, migration, and differentiation, among others. This article aims to review some of the recent progress that has been made in modeling mechanosensing in cell-matrix interactions at different length scales. The issues discussed include specific interactions between proteins, the… CONTINUE READING