Modeling, simulation and operation of a simulated moving bed for continuous chromatographic separation of 1,1′-bi-2-naphthol enantiomers

@article{Pais1996ModelingSA,
  title={Modeling, simulation and operation of a simulated moving bed for continuous chromatographic separation of 1,1′-bi-2-naphthol enantiomers},
  author={L. Pais and J. Loureiro and A. Rodrigues},
  journal={Journal of Chromatography A},
  year={1996},
  volume={769},
  pages={25-35}
}
  • L. Pais, J. Loureiro, A. Rodrigues
  • Published 1996
  • Materials Science, Chemistry
  • Journal of Chromatography A
  • Abstract The objective of this paper is to study the separation of enantiomers of 1,1′-bi-2-naphthol in 3,5-dinitrobenzoyl phenylglycine bonded to silica gel, using heptane–isopropanol (72:28) as eluent by simulated moving bed chromatography (SMB). A model for the prediction of the cyclic steady state performance of the SMB, based on the analogy with the true moving bed, is developed assuming axial dispersion flow, linear driving force approximation for intraparticle mass transfer and… CONTINUE READING
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