Model selection in binary trait locus mapping.

  title={Model selection in binary trait locus mapping.},
  author={Cynthia J. Coffman and Rebecca W. Doerge and Katy L. Simonsen and Krista M Nichols and Christine Duarte and Russell D. Wolfinger and Lauren M. McIntyre},
  volume={170 3},
Quantitative trait locus (QTL) mapping methodology for continuous normally distributed traits is the subject of much attention in the literature. Binary trait locus (BTL) mapping in experimental populations has received much less attention. A binary trait by definition has only two possible values, and the penetrance parameter is restricted to values between zero and one. Due to this restriction, the infinitesimal model appears to come into play even when only a few loci are involved, making… CONTINUE READING


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