Corpus ID: 218684396

Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy.

@article{Hoehme2020ModelPF,
  title={Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy.},
  author={S. Hoehme and R. Gebhardt and J. Hengstler and D. Drasdo},
  journal={arXiv: Tissues and Organs},
  year={2020}
}
Partial hepatectomy (PHx) is a surgical intervention where a part of the liver is removed. Due to its extraordinary capacity to regenerate, the liver is able to regenerate about two-thirds of its mass within a few weeks. Nevertheless, in some patients regeneration fails. Understanding the principles and limitations underlying regeneration may permit to control this process and prospectively improve the regeneration. Here, we established a simulation model to mimic the process of regeneration in… Expand

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