Model of vasculogenesis from embryonic stem cells for vascular research and regenerative medicine.

@article{Nakagami2006ModelOV,
  title={Model of vasculogenesis from embryonic stem cells for vascular research and regenerative medicine.},
  author={Hironori Nakagami and Namika Nakagawa and Yasushi Takeya and Katsunobu Kashiwagi and Chisato Ishida and S Hayashi and Motokuni Aoki and Kunio Matsumoto and Toshikazu Nakamura and Toshio Ogihara and Ryuichi Morishita},
  journal={Hypertension},
  year={2006},
  volume={48 1},
  pages={
          112-9
        }
}
Embryonic stem (ES) cells are highlighted as promising cell sources for regenerative medicine. Here, we focused on providing the platform that forced ES cells to reproduce the vascular organization process, leading to efficiency and safety evaluation as preclinical testing of biological agents. Murine ES cell-derived embryoid bodies on matrigel, but not collagen or gelatin, could be differentiated into sprouting blood vessels without the addition of growth factors. The expression of endothelial… CONTINUE READING

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