Model of reticuloendothelial iron metabolism in humans: abnormal behavior in idiopathic hemochromatosis and in inflammation.

@article{Fillet1989ModelOR,
  title={Model of reticuloendothelial iron metabolism in humans: abnormal behavior in idiopathic hemochromatosis and in inflammation.},
  author={George Fillet and Yves Beguin and Laura Baldelli},
  journal={Blood},
  year={1989},
  volume={74 2},
  pages={844-51}
}
Iron transport in the reticuloendothelial (RE) system plays a central role in iron metabolism, but its regulation has not been characterized physiologically in vivo in humans. In particular, why serum iron is elevated and RE cells are much less iron-loaded than parenchymal cells in idiopathic hemochromatosis is not known. The processing of erythrocyte iron… CONTINUE READING